News for Healthier Living

Understanding Neurological Diseases: Crucial Interactions Come to Light

Scientists led by UdeM's Frederic Charron reveal significant interactions at the heart of neurons.

December 17, 2024

December 21 2024

• Tips for Spending Holiday Time With Family Members Who Live with Dementia

December 20 2024

• Resolving To Exercise More In The New Year? Experts Say Ease Into It To Make It A Habit And Avoid Injury
• UC Davis Researchers Help Decode the Cause of Aggressive Breast Cancer in Women of Color
• Potential Culprit Identified in Lingering Crohn's Disease Symptoms
• Sutures and Power Tools: Cedars-Sinai Orthopaedics Inspires Young Women
• Stor4Build Heats Up Thermal Energy Storage Solutions for Buildings, Grid
• The Secret Life of ALAS1: How a Basic Science Discovery Could Pave the Way for Better siRNA Therapies
• The Neiman Imaging Comorbidity Index Proves Effective for Risk-Adjustment Across Medicare, Medicaid and Privately Insured Populations
• First Dual Chamber Leadless Pacemaker Implanted in a Child
• Tainted Cucumbers Now Linked to 100 Salmonella Cases in 23 States
• Automation of Nuclear Chemistry Processes Leads to More Efficient Production of Astatine for Cancer Therapy
• Check Your Pantry, Lay's Classic Potato Chips Recalled Due to Milk Allergy Risk
• Norovirus Sickens Hundreds on Three Cruise Ships: CDC
• Not Just Blabber: What Baby's First Vocalizations and Coos Can Tell Us
• What's the Link Between Memory Problems and Sexism?
• Supreme Court to Decide on South Carolina's Bid to Cut Funding for Planned Parenthood
• Antibiotics Do Not Increase Risks for Cognitive Decline, Dementia in Older Adults, New Data Says
• A New Way to Treat Sjögren’s Disease? Researchers Are Hopeful
• Some Abortion Pill Users Surprised By Pain, Study Says
• Who is At Risk For Cybercrime?
• Transforming Smiles, Transforming Lives: Free Dental Care Empowers Opportunity Center Residents at Hopeful Smiles Event
• Older Age Linked to Increased Complications After Breast Reconstruction
• AI's New Move: Transforming Skin Cancer Identification
• Nursemaid Elbow 101

December 19 2024

• A Steady Hand Close To Home - There's No Better Gift
• Faster Lung Function Decline in Cystic Fibrosis Linked to High Sputum Levels of Pf Bacteriophage
• Study Uses High-Tech Golf Simulator to Determine How Joint Replacement Surgery Affects Players' Game
• By Looking at Individual Atoms in Tooth Enamel, UW and PNNL Researchers Are Learning What Happens to Our Teeth as We Age
• Cedars-Sinai, UCSF Experts Steer the Development of Stem Cells to Regenerate and Repair Organs
• HELLP and Heredity Collide in a Remarkably Rare Pregnancy Journey
• FDA Updates Meaning of 'Healthy' on Food Labels
• Combining Long- and Short-Read Sequencing in Single Cells Reveals New mRNAs in Neurodegenerative Diseases
• Cedars-Sinai Chuck Lorre Allied Health School Steps Closer to Welcoming First Students
• New Findings Expand Genetic Knowledge of Autism Underpinnings
• It's All In How You Structure Your Resolution. Mental Health Experts Available On Why Most People Fail With Their New Year's Resolutions, And How To Improve Your Odds In 2025
• A Pioneer in Brain Imaging Wins NJIT's 2024 Excellence in Research Award
• 1 in 5 Adults With Long Covid Struggle With Daily Activities
• FDA Says Shortage of GLP-1 Tirzepatide Is Over
• Cold Weather Deaths Keep Rising for Americans
• California Declares Bird Flu Emergency as Outbreak in Cows Continues
• DOJ Alleges CVS Facilitated Unlawful Sales, Violating Federal Opioid Regulations
• Freeze Frame: How to Stop Winter Bone and Joint Injuries in Their Tracks
• Sleep Apnea May Change Parts of Brain, Speed Aging
• New Youth Mental Health Program Shows Promise
• Are You At Risk for Dementia? New Blood Test May Tell
• Multiple Chronic Conditions Can Add Up to Kidney Trouble
• A New Way to Diagnose Painful 'Wear-and-Tear' Arthritis?
• Early Research Points to Possible New Parkinson's Drug
• Milk Cereal Drinks for Infants May Trigger Weight Gain
• U.S. Life Spans Rebound from Pandemic Lows, Helped by Drop in Fatal Overdoses
• Dry January and Beyond, Why Experts Say It May Be The Best Way To Drink To Your Health
• 'Tis the Season for Safety and Holiday Cheer
• A Brighter Outlook: New Research Defines IOL Exchange Criteria
• Hematology, Oncology, Neuro-Oncology Stem Cell Transplantation Updates: Winter 2024
• Reducing Dose of Popular Blood Thinners May Limit Risk of Future Bleeding
• Targeting a Brain Enzyme to Curb Obesity
• The Surprising Role of Gut Infection in Alzheimer's Disease

December 18 2024

• Houston Methodist Scientists Make Surprising Discovery Pinpointing When Good Cholesterol Becomes Harmful
• MD Anderson Research Highlights for December 18, 2024
• Researchers Find New Way to 'Starve' Prostate Cancer Tumors at the Cellular Level
• Roswell Park Team Discovers New Treatment Target for Neuroendocrine Prostate Cancer
• Rutgers Researcher Receives a $2 Million Five-Year NIH Grant to Advance Nucleic Acid Therapies
• Improvement Initiative Increased Well-Being and Reduced Inefficiencies for Surgical Residents
• MSK Research Highlights, December 18, 2024
• Patient Hospitalized in Louisiana With First U.S. Case of Severe Bird Flu
• Researchers Identify Key Driver of Fibrosis in Crohn's Disease
• Supporting Neurodivergent Loved Ones During the Holidays
• Runners Who Wear These Shoes Are More Likely to Get Injured
• Sleep Apnea Linked to Changes in the Brain
• Good News for Seniors: Study Finds Antibiotics Not Linked to Dementia
• New Discovery by Case Western Reserve University School of Medicine Researchers Provides Hope in Fighting Drug-Resistant Malaria
• FDA: Veozah, First Hormone-Free Hot Flash Drug, Issued Black Box Warning
• Are Microplastics In the Air Putting Your Fertility At Risk?
• Non-heterosexual Women Report Better Sexual Functioning During Midlife
• Act Fast and You Can Still Enroll In An ACA Healthcare Plan for 2025
• Some Breast Cancer Patients May Not Need Post-Op Chest Wall Radiation
• With Correct Measurements, Wine Really May Protect Heart
• U.S. Teen Drug, Alcohol Use Remains at Low Levels
• For Hispanic Women, Holidays Can Bring Mixed Body Image Messages
• Artificial Sweetener Use Tied to Less-Healthy Diets
• How Sound and Vibration Converge in the Brain to Enhance Sensory Experience
• Six Things to Look for in a Pediatric Oncologist
• Virtual Escapes, Real Benefits: Open-World Games Boost Mental Well-Being
• Vagus Nerve Stimulation Relieves Severe Depression
• People From Some Racial and Ethnic Groups May Face Barriers to Obtaining Obesity Medications
• Medicaid Patients in States with Relatively Higher Medicaid Reimbursement Are More Likely to Receive Imaging
• Socioeconomic Inequality: A Silent Killer for Cancer Patients' Lifespan
• Potentially Harmful Bacteria Slip Through Antimicrobial Showerheads
• Study Supports New Blood-Based Biomarker to Detect Early Brain Changes Leading to Cognitive Impairment and Dementia
• Genetic Testing Changes Course of Care in Children with Neurodevelopmental Conditions
• Rethinking Value Assessment for Orphan Drugs

December 17 2024

• How UNC's Chronic Pancreatitis and Autologous Islet Cell Transplant Program Provides Holistic, Life-Changing Care
• Researchers Create Gene Therapy with Potential to Treat Peripheral Pain Conditions
• Donations to Cardinal Bernardin Cancer Center "Tree of Love" Honor Cancer Patients and Caregivers
• MSU Researchers Use Virtual Reality to Modernize Health Care Training
• New Virtual Reality-Tested System Shows Promise in Aiding Navigation of People with Blindness or Low Vision
• Risk Factors for Inadequate Bowel Preparation and More in the December Issue of The American Journal of Gastroenterology
• Majority of People say Exercising Helps Improve Sleep
• Genetic Testing Moving Into the Mainstream, UTSW Study Finds
• University Hospitals Haslam Sports Innovation Center Makes First Investments in Sports Medicine Innovation
• December Research Tip Sheet
• Understanding Neurological Diseases: Crucial Interactions Come to Light
• Team Sports Score Big Points for Your Child's Brain, Study Finds
• U.S. Woman Living Healthy With Kidney Sourced From Pig
• Feeling 'Techno-Strain' From Work? You're Not Alone
• Top Cancer Research Advances at MSK in 2024
• Denser Urban Neighborhoods Get People Walking
• Study Supports HPV Self-Testing for Cervical Cancer Screening
• Scientists Identify Genes That Shape People's Teeth
• Taxi Drivers' Brains May Leave Them Less Vulnerable to Alzheimer's
• Allergies Have You Stuffed Up? Nose Fungi May Be to Blame
• Could MRI Spot 'Pre-Cancer' Lesions of the Pancreas?
• Tiny Robots, Big Impact: Revolutionizing Infertility Treatment with Magnetic Microrobots
• Biased Language in Clinical Handoffs May Negatively Impact Patient Care
• For Black Youth With Autism, Encounters With Police Bring Special Dangers
• Sylvester Cancer Tip Sheet for Dec. 2024
• UC Irvine Researchers Reveal a Revolutionary New Approach for 3D CT Imaging From a Single X-ray Projection

December 16 2024

• Healthy Eating Habits to Carry You Through the Holidays
• NYU Tandon Researchers Create Microchips Capable of Detecting and Diagnosing Diseases
• Governor Hochul Celebrates the Opening Of New York's First Cell and Gene Therapy Hub at Roswell Park Comprehensive Cancer Center in Buffalo
• Threat of Abrupt Mortality Events Keeps Endangered Monkey Population at Risk, Despite Decades of Growth
• UNLV Expert: Regenerating the Brain After a Stroke
• Breakthrough in Treatment Approach Showing Promise in the Fight Against Glioblastoma, the Deadliest and Most Aggressive Type of Brain Cancer
• Long COVID's Effects on Employment: Financial Distress, Fear of Judgment
• Consumers of Diet Beverages and Sugar Substitutes Have Lower Quality Diets, New Study Says
• Supporting a Grieving Loved One on Holidays and Special Occasions: Practical Tips From a Clinical Psychologist
• AASM Advocates for Permanent Sleep Telehealth Services to Enhance Patient Care Nationwide
• Blue Holiday: How to Cope With Sadness Amid Holiday Cheer
• What's Your Health Forecast? Expert Explains Science Behind Personal Guides to Well-Being
• Fast, Rewritable Computing with DNA Origami Registers
• 15 Million U.S. Adults Are at Elevated Risk for Heart Failure
• Study Exposes Critical Need for More Research on Health Disparities in Treatment of Chronic Conditions
• As Daily Steps Rise, Depression Levels Fall
• Patient in Louisiana Hospitalized With First Bird Flu Case in That State
• Texas Sues NY Doctor for Prescribing Abortion Pill by Telehealth
• Trump Says He'll Try to Rid U.S. of Daylight Saving Time
• Staphylococcus Aureus Thwarts Vaccines by Turning on a Protein That Halts Immune Response
• Bribing Kids With Holiday Gifts Popular With Parents, Poll Says
• Colon Cancer Rates Are Up Among the Young Worldwide
• Omega-3 Rich Diet May Help Slow Prostate Cancer Growth
• Friendships Are Especially Powerful Late in Life, Poll Says
• AI Guided Breath Test Could Speed COPD Diagnosis
• Study Supports Tamoxifen for DCIS Early Breast Cancers
• Prenatal Exposure to Air Pollution May Hurt Baby's Brain
• CHLA's SLAY Program Receives $2 Million Grant to Support Substance Use Prevention and Leadership Training for High School Students
• Naughty or Nice? Many Parents Rely on Threats to Manage Misbehavior - From No Dessert to No Santa

December 15 2024

• Ditch TV and Read a Book: UniSA Research Delivers Best Moves to Reduce Dementia Risk

December 14 2024

• Wintertime Is Prime Time for Head Lice: What Parents Need to Know

December 13 2024

• SLU Primary Care Sports Physician Explains the Concussion Gender Gap
• New Study Shows Mobile Mammography Reach is Highest in Underserved Groups with Low Breast Cancer Screening Adherence
• Memorial Sloan Kettering Physician-Scientists Develop Innovative Multimodal Machine Learning Model That Improves Prediction of Metastatic Breast Cancer Treatment Options
• Cancer: Combating Chemotherapy Resistance
• Generic Platinum Chemotherapy Shortages Did Not Increase Deaths
• U.S. Adult Obesity Rate Fell in 2023, as Use of GLP-1 Meds Rose
• Exposure to Remote Wildfire Smoke Drifting Across the U.S. Linked to Increased Medical Visits for Heart and Lung Problems
• A Low Omega-6, Omega-3 Rich Diet and Fish Oil May Slow Prostate Cancer Growth, UCLA Study Finds
• Eat Less Meat, More Beans & Lentils for Protein, New USDA Guidelines Say
• Newer Drug Could Be Advance Against Tough-to-Treat Breast Cancers
• Blood Test Might Alert Doctors to Problem Drinking
• 'Watch and Wait' May Equal Active Treatment for Early DCIS Breast Cancers, Studies Find
• Breast, Ovary Removal Can Lengthen Lives of Women With Breast Cancer Genes
• Air Pollution Could Be Raising Your Odds for a Blood Clot
• In Mouse Studies, New Hope Against a Dangerous Complication of Pregnancy
• Caregiving Stress Can Raise Blood Pressure for Young Black Women
• Who's Most Likely to Get the Mpox Shot in U.S.?
• Reiki May Help Ease the Pain of Cancer Treatment
• Helmsley Charitable Trust Awards $3 Million Grant to Research Epithelial Healing in Crohn's Disease
• Light-induced Gene Therapy Disables Cancer Cells' Energy Center
• A Pediatric Program Helping Adults Through Cardiovascular Disease, Surgery
• AI Shaping the Future of Breast Cancer Risk Prediction

December 12 2024

• After traumatic dog bite, surgeons rebuild woman's nose
• Discovery of Gene Linked to High-Altitude Adaptation May Transform Blood Cancer Care
• UTSW Research: Python Guts, Emergency Room Visits, and More
• Metal Scrap Upcycled into High-Value Alloys with Solid Phase Manufacturing
• Roswell Park Team Identifies Factors That Boost Effectiveness of Immunotherapy in Recurrent Ovarian Cancer
• Social Risks Impede Cancer Screening, Even with Access to Care
• Asthma More Prevalent Among Children with Primary Ciliary Dyskinesia
• University Hospitals Robust Robotic Cardiac Surgery Program Treats 100+ Patients
• Can Bacteria Handle Stress? Study Reveals How Combined Stressors Overwhelm Harmful Bacteria
• Too Many U.S. Babies Still Sleep in Positions That Raise SIDS Risk
• Too Much Screen Time Harms Preschoolers' Sleep, Behavior
• U.S. Overdose Deaths Fell 17% in Just One Year
• Study Warns That Cats Might Be Bird Flu Carriers
• Only a Third of U.S. Kids Have Gotten Flu Shots
• Expert Povides Four Ways to Keep Your Kids From Becoming Picky Eaters
• Mystery Illness Outbreak in Congo May Be Malaria
• FDA Asks Biden Administration to Limit Nicotine in Tobacco Products
• Blood Test Might Help Doctors Spot Multiple Diseases
• Blood Pressure Ups & Downs May Harm Seniors' Thinking
• Unhealthy, Ultra-processed Foods Now Half of Calories Americans Eat at Home
• Staying Fit Can Keep Seniors' Brains Sharp
• Preteen, Teen Smoking Can Injure The Young Heart
• Ditch That Itch: Early Findings Offer Hope Against Range of Skin Conditions
• Brain Tumors Hijack Circadian Clock to Grow
• With a Little Help From Their Friends: Poll Shows Role of Close Friendships in Older Adults' Health
• Improving Health in Rural Areas Takes Community
• New Years Resolutions? No Thanks! Tips on Controlling Allergies and Asthma? Yes, Please
• Gene Expression Differences in Fat Tissue May Inform Targeted Treatment for Obesity
• How a New Test Is Transforming Care for Retinoblastoma

December 11 2024

• ACS Study Finds Early-Onset Colorectal Cancer Cases Surge Globally
• Is Ozone Pollution Harming Unborn Children?
• Could a Key Protein Lead to New Therapies for Wilms Tumor?
• Innovative Surgery Preserves Limb Growth for Childhood Bone Cancer Patients
• Fluctuating Blood Pressure Tied to Problems with Thinking Skills
• From Poison to Panacea
• Study Reveals How Unexpected Shifts in Cell Populations Are Revising Our Understanding of the Aging Process
• Jamie Foxx Reveals He Had Brain Bleed in 2023
• Bird Flu in California Child Similar to Strain Seen in Livestock
• Rutgers Health Forms Corps to Clear the Air About Asthma
• More Than 50% Americans Give to Charity at Checkout, Survey Shows
• The Global Divide Between Longer Life and Good Health
• A New Class of Antivirals Could Help Prevent Future Pandemics
• Genital Herpes Affects 1 in 5 Younger Adults Worldwide
• 'Brain Boost' From Today's Exercise May Linger Through Tomorrow
• What Works Best to Help Young Vapers Quit?
• Parents' Smoking Could Raise Risk for MS in Kids
• Car Height, Not Just Speed, Matters When Pedestrians Are Hit
• Are You a 'Late Gift-Giver'? Study Finds Folks Mostly Don't Mind
• 'Ableism' Prevents Many Americans From Getting Mental Health Care
• Removing, Storing Patient's Blood Before Liver Surgery Helps Avoid Transfusions
• Women With Cancer Can Safely Use Rogaine to Curb Hair Loss
• Mount Sinai Researchers Move Closer to a Cure for Diabetes
• Smoking Tobacco From Childhood Can Cause Premature Heart Damage
• Low on Energy? Expert Recommends a Natural Boost Over Caffeine
• Esophageal Cancer: Global Burden Intensifies, Calls for Urgent Action
• Unlocking the Secrets of the Mind
• Breast Cancer Alert: Study Finds Post-35 Weight Gain Raises Risk
• Battling Breast Cancer: New Insights Into Angiogenesis and Drug Resistance
• First Full Characterization of Kidney Microbiome Unlocks Potential to Prevent Kidney Stones

December 10 2024

• Task Force Supports Women Over 30 Collecting Samples for Cervical Cancer Screening
• Filling Out the Roadmap for Faster Drug Approvals
• More Women Are Being Diagnosed With Breast Cancer at Later Stages
• Opioid Abuse Can Change the Brain
• Ultra-processed Foods May Raise Colon Cancer Risk
• Mpox Vaccination Rates Highest Among Cisgender Sexual Minority Men
• Fighting Prostate Cancer, From Farm to Table, at MSU
• Research Shows New Treatment Could Delay Cancer Progression in Patients with High-Risk Smoldering Multiple Myeloma
• Wildfire Smoke Is Choking America's Cities -- Is Yours on the List?
• Group of Nobel Laureates Press Senate to Reject Kennedy's Nomination
• Neonatology News December 2024
• Using Stem-Cell Transplants to Treat Blindness
• Recommendations May Help Reduce Delirium in Older Patients Having Surgery
• Ultraprocessed Foods Account for More than Half of Calories Consumed at Home
• GLP-1 Meds May Lower Clot Risk in People With Diabetes
• 1 in 6 U.S. Adults With Asthma Can't Afford Meds
• Teens, Booze and E-Scooters: A Rising Threat as Injuries Crowd ERs
• Gene Therapy Reverses Heart Failure in Pig Trials
• SABCS: Improved Survival for Advanced Breast Cancer, Using Genomics to Identify Patients with High Risk of Recurrence, How Race/Ethnicity Influence the Risk of Heart Failure in Early-Stage Breast Canc
• Americans Are Uninformed About and Undervaccinated for HPV
• Bed Sores Can Slow Neurological Recovery After Spinal Cord Injury
• Rethinking the Brain Pacemaker: How Better Materials Can Improve Signals
• Geriatric Surgery Verification Program Can Improve Outcomes for Older Cancer Patients in Community Hospitals
• Using 'Biological Age' to Predict Early Colorectal Cancer Risk
• Health Tips and Lookouts to Help You Power Through the Holiday Season
• Early Life Exposure to Toxic Chemicals May Cause Behavioral, Psychological Problems
• New Targets for Diabetic Kidney Disease Could Prevent End Stage Kidney Failure
• New Gene Therapy Reverses Heart Failure in Large Animal Model
• Almost Half of Young Vapers Are Able to Stop with Quitline Help
• After a Divisive Election, Most U.S. Adults Ready to Avoid Politics This Holiday

December 9 2024

• EMBARGOED: Dozens of Presentations Advance Multiple Myeloma Research at the 2024 American Society for Hematology (ASH) Meeting
• ASH Presentation: Study Shows That Genetic Mutations Accumulate in Smokers with Myelodysplastic Syndromes and Worsen Outcomes
• ASH: Triplet combination regimens demonstrate high response rates in multiple leukemias
• Could Venetoclax Improve Outcomes of CAR T for Patients with Resistant B-Cell Lymphomas? New Insights at ASH
• 1 in 3 Older Americans Say They Feel Lonely, Poll Finds
• Toxoplasma Gondii Parasite Uses Unconventional Method to Make Proteins for Evasion of Drug Treatment
• ASH: Monoclonal Antibody Therapy Improves Survival in Cancer-Associated Hyper-Inflammatory Disorder
• Lighting Campus for Hope: A Winter Wonderland of Resilience and Community
• Considering Social and Genetic Factors in Addition to Clinical Factors Improves Prediction of Heart Disease Risk
• Experts Debate Management of Patient with Gastroesophageal Reflux Symptoms
• Controlling Infectious Disease Between Wildlife and Livestock on Shared Rangeland
• Children's Hospital of Philadelphia Researchers Find Precision Medicine Treatment Delivers Strong Results for Infantile Fibrosarcoma and Other Solid Tumors
• EPA Study Finds That U.S. Public Schools with the Highest Potential Exposure Risk to Air Toxics Have Higher Proportions of Disabled Latino, Hispanic, and Asian Children
• A Healthy Diet Helps the Weighty Battle with Chronic Pain
• Grad Student Investigates Intersection of Gender and Neurodiversity in Academic Spaces
• Trump Says RFK Jr. Free to Revisit Discredited Autism/Vaccine Link
• What Motivates Americans to Eat Less Red Meat?
• Toxic Air in Texas High Schools
• Illinois Researchers Investigate Weaponizing Bacterial Viruses to Combat Superbugs
• EPA Bans Two Solvents Linked to Cancer
• How a Tabletop Robot May Revolutionize Physical Therapy Delivery
• Global Warming's Heat Is Killing the World's Young
• There's a 'Sweet Spot' for Daily Sugar Intake & Heart Health
• Dolphins Are Testing Positive for Fentanyl
• One Type of Blood Pressure Med May Help Prevent Post-Stroke Epilepsy
• Keto Diet Supplement Could Boost a Cancer Treatment's Effectiveness
• Ovary Removal Could Greatly Raise Some Women's Odds for Alzheimer's
• Long COVID Is Taking Toll on Americans' Finances
• The VR Technologist Will See You Now
• High-Fiber Diet May Prevent a Blood Cancer in People at High Risk
• Loneliness and Isolation: Back to Pre-Pandemic Levels, but Still High, for Older Adults
• Why the FDA Should Move Fast to Regulate Nicotine Pouches
• Woods Hole Oceanographic Institution and Partners Discover New Ocean Predator in the Atacama Trench
• Precision Diabetes Management: Glucose-Triggered Insulin Delivery Membrane
• New Study Reveals Key Insights on Sarcoma Rates in Military vs. Civilian Men
• Children's Hospital of Philadelphia Researchers Find Rotavirus Vaccine is Safe for Use in NICU Babies

December 8 2024

• Resistance Training Can Reduce Fatigue, Pain in Multiple Myeloma Patients, Roswell Park Team Shows
• Everything You Need to Know About Shingles & the Shingles Vaccine
• Roswell Park Experts Report Insights on CAR T for Follicular Lymphoma, KEYNOTE-667 Combo in Hodgkin Lymphoma
• ASH 2024: Antibody Shows Encouraging Results for Treating High-risk Follicular Lymphoma and Marginal Zone Lymphoma
• Multi-Center Study Shows Education Level, Income Impact Access to Stem Cell Transplantation for Acute Myeloid Leukemia Patients